What’s the Difference Between Botox vs. Xeomin: Which is Best For You in Sacramento

Have you ever looked in the mirror and been saddened by the transformation of your once youthful appearance? Time passes quickly, and years of life experience can manifest on the face at a faster rate than on other body parts, particularly if you are a facial expressive individual. Wrinkles, crow’s feet, forehead lines and frown lines are a natural part of ageing, even with proper skincare and skin maintenance. Thankfully, aesthetic treatments are available to provide smoother skin, fewer wrinkles and a more youthful look. These treatments include injectable treatments such as Xeomin or Botox, which can soften and temporarily remove heavy lines and wrinkles. This article will discuss the differences between the two treatments to help you determine which one is best suited for smoothing out wrinkles and providing a more youthful and attractive appearance.

What are Xeomin and Botox?


Xeomin (incobotulinumtoxinA) is an injectable medication that contains botulinum toxin, which comes from the bacteria Clostridium botulinum. This is the same bacteria that causes botulism, a life-threatening illness that affects your nerves, breathing, and muscles. Xeomin is manufactured by Merz Pharmaceuticals and officially approved by the U.S. Federal Drug Administration (FDA) in 2010 as the newest neuromuscular blocker on the market for various cosmetic and medical procedures.


Botox (onabotulinumtoxinA), manufactured by Allergan, is also an injectable medication that’s made from botulinum toxin, as one of the most popular non-invasive injectable treatments in the United States. Botox was first approved by the FDA (U.S. Food and Drug Administration) to treat certain medical conditions in 1985 and approved for cosmetic use in 2002.

How do Xeomin and Botox treat wrinkles?

Xeomin and Botox are both neuromodulators that are used to reduce the appearance of wrinkles and fine lines. They are both injected into the muscles that cause wrinkles, and they work by blocking the release of acetylcholine, a neurotransmitter that is responsible for muscle contraction. This causes the muscles to relax, which smooth out the skin and reduces the appearance of wrinkles.

How long does Xeomin or Botox last?

The effects of both Xeomin and Botox are temporary, typically lasting between 3 to 4 months. Some patients report that Xeomin’s results can extend up to 6 months, offering a longer duration between treatments. The longevity of results varies from person to person and depends on the area treated and the individual’s metabolism.

How many units Xeomin vs. Botox are needed?

The dosing between Xeomin and Botox are generally considered equivalent in terms of the amount required to achieve desired results. The exact number of units needed will depend on the treatment area and the individual’s specific goals, which should be determined in consultation with our qualified healthcare provider.

Are there any differences with the procedures?

The procedures for administering Xeomin and Botox are very similar, involving injections into targeted facial muscles. Both treatments are quick, often completed within minutes, and require no downtime, allowing patients to return to their daily activities immediately.

Are there any differences in the effectiveness?

Both Xeomin and Botox are effective in reducing the appearance of wrinkles and fine lines. The choice between the two often comes down to how an individual’s body responds to the treatment and their personal preference. Some may find that they achieve better or faster results with one product over the other.

What are the common side effects of Xeomin or Botox?

Common side effects for both treatments include temporary bruising, swelling, or redness at the injection site. Rarely, patients may experience more significant side effects such as muscle weakness, allergic reactions, or headache. The risk of adverse effects underscores the importance of receiving these treatments from an experienced and qualified provider.

What makes Xeomin and Botox different?


The main difference between Xeomin and Botox is their formulation. Xeomin is a highly purified form of botulinum toxin type A, while Botox contains other proteins in addition to the active ingredient. This formulation difference may reduce the likelihood of Xeomin causing allergic reactions compared to Botox.

Complexing Protein

Another difference between Xeomin and Botox is that Xeomin is manufactured without a complexing protein, while Botox is manufactured with a complexing protein. The complexing protein in Botox helps to ensure that the product is distributed evenly throughout the muscle, which can help to produce more consistent and predictable results. However, the complexing protein may also increase the risk of side effects, such as allergic reactions and muscle weakness.

Duration of Results

The effects of both Xeomin and Botox typically last for several months, but some studies have shown that Xeomin may last slightly longer. This is likely due to the fact that Xeomin is a more purified form of botulinum toxin type A. When Xeomin is injected into the muscles, it takes longer for the body to break it down. This means that Xeomin may continue to block nerve signals to the muscles for a longer period of time than Botox.

Is Xeomin more affordable than Botox?

At Medspa of Sacramento, Xeomin is typically more affordable than Botox. Our Xperience+ loyalty program offers $50 OFF toward qualifying treatments. Xeomin pricing is based on the number of units of injection required for treatment, or the areas that require treatment.

What should you avoid after Xeomin treatment?

Xeomin for Frown Lines – 14 days before and after

Rubbing or Massaging the Treatment Area

Xeomin is a neuromodulator that works by blocking nerve signals to the muscles. Rubbing or massaging the treated area can spread the Xeomin to other areas of the face, which can cause the muscles in those areas to relax. This can lead to unwanted results, such as a droopy eyelid or an uneven smile.

Using Certain Skincare Products

Some skincare products, such as alpha hydroxy acids (AHAs) and beta hydroxy acids (BHAs), can irritate the skin and make the side effects of Xeomin worse. It is best to avoid using these products for 24-48 hours after treatment.

Alcohol Consumption

Alcohol is a vasodilator, which means that it widens the blood vessels. This can increase blood flow to the injection site, which can make bruising and bleeding more likely. Additionally, alcohol can dehydrate the skin, which can make it more fragile and susceptible to bruising.

Heat and Sun Exposure

Avoid prolonged exposure to heat, including hot baths, saunas, and sunbathing, for at least 24 hours after the treatment. These can increase the risk of swelling or bruising. In the event of sun exposure, it is recommended to wear a hat and apply appropriate sunscreen to protect the skin.

Deciding between Xeomin or Botox for you

Choosing between Xeomin and Botox involves a personalized discussion with our providers, considering your aesthetic goals, treatment history, and any potential for allergic reactions. At Medspa of Sacramento, we’ve chosen Xeomin as our preferred neurotoxin, and for good reason. Its purity, stemming from a unique formulation that strips away unnecessary proteins, not only makes it a cleaner option but also contributes to its affordability. Our patients consistently report experiencing quicker results with Xeomin compared to Botox. Additionally, they delight in the longevity of its effects outlasting those of its counterparts. This combination of purity, rapid action, extended duration, and cost-effectiveness makes Xeomin a standout choice.

How do I book Xeomin treatment at Medical Spa in Sacramento?

Selecting the perfect place for your anti-wrinkle treatments is crucial, and Medspa of Sacramento stands out as the ideal choice. We’re proud to offer both Xeomin and Botox, ensuring a broad array of options that are customized just for you. In our reviews, patients tell us that we are the best medspa near you in Sacramento because we’re dedicated to designing personalized treatment with your desires and price in mind.

Book online for your FREE CONSULTATION to find out which is right for you.

Contact us at (916) 430-5014 or email@medspaofsacramento.com today!

Disclaimer: Results may vary from person to person. Consult with our medical injectors to determine the best treatment for your specific needs.